Healthcare Professionals

Source Control Through Rapid Extracorporeal Blood Filtration of Pathogens

Seraph 100 reduces the blood concentration of SARS-CoV-2, the virus that causes COVID-19. Clinicians have reported improved outcomes, hemodynamic stability, reduction of vasopressors and fractionally inspired oxygen, and avoidance or reduced time of mechanical ventilation.^{1, 2, 3}

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The Seraph 100:

Reduces COVID-19 through pathogen adsorption
Surface chemistry mimics the endothelium’s pathogen binding qualities

Must-Read Publications:

Publications

1.	Chitty SA, Mobbs S, Rifkin BS, et al. A Multicenter Evaluation of the Seraph 100 Microbind Affinity Blood Filter for the Treatment of Severe COVID-19. Crit Care Explor J. 2022; 4(4):1-11. DOI: 10.1097/CCE.0000000000000662
2.	Schmidt JJ, Borchina D, van’t Klooster M, et al. Interim Analysis of the COSA (COVID-19 Patients Treated with the Seraph 100 Microbind Affinity Filter) Registry. Nephrol Dial Transplant. 2022; 37(4):673-680. doi: 10.1093/ndt/gfab347
3.	Stoffel S, Boster J, Jarrett Z, et al. Single-Center Experience With the Seraph-100® Microbind® Affinity Blood Filter in Patients With SARS-CoV-2 Infection and Septic Shock at a Military Treatment Facility, Military Medicine, 2023;00(0/0):1:1-5 doi: 10.1093/milmed/usad063

Seraph 100 in the Field

Seraph 100 Microbind Affinity Blood Filter Technology

Seraph 100 is being used in hospitals across the United States, including several military hospitals. Several hospitals have presented their findings:

Brooke Army Medical Center: Single-Center Experience With the Seraph 100 in Patients With SARS-CoV-2 Infection and Septic Shock at a Military Treatment Facility

Walter Reed Medical Center: Treatment for Severe Coronavirus Disease 2019 With the Seraph-100 Microbind Affinity Blood Filter

Brooke Army Medical Center: USU COVID – 19 Clinical Performance Improvement Conference #19 Severe ARDS secondary to COVID Pneumonia

Dwight D. Eisenhower Army Medical Center: USU COVID – 19 Clinical Performance Improvement Conference #19 Seraph 100 Case Reports

Providers Using Seraph 100

in the United States

For guidance on the use of Seraph 100 on COVID-19 patients, please follow the links below:

EUA Instructions for Use

EUA Health Care Providers Fact Sheet

EUA Patient Fact Sheet

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